Department of Immunology,
Graduate School of Biomedical and Health Sciences

業績

2021

1. K Yoshioka, H Nagahisa, F Miura, H Araki, Y Kamei, Y Kitajima, D Seko, J Nogami, Y Tsuchiya, N Okazaki, A Yonekura, S Ohba, Y Sumita, K Chiba, K Ito, I Asahina, Y Ogawa, T Ito, Y Ohkawa and Y Ono. 2021. Hoxa10 mediates positional memory to govern stem cell function in adult skeletal muscle. Sci Adv 7:eabd7924. DOI:10.1126/sciadv.abd7924

2. K Yoshioka, Y Kitajima, D Seko, Y Tsuchiya and Y Ono. 2021. The body region specificity in murine models of muscle regeneration and atrophy. Acta Physiol (Oxf) 231:e13553. DOI:10.1111/apha.13553

3. T Yasuda, Y Saito, C Ono, K Kawata, A Baba and Y Baba. 2021. Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells. Sci Rep 11:5524. DOI:10.1038/s41598-021-84786-6

4. S Yamaguchi, H Hamana, K Shitaoka, K Sukegawa, T Nagata, A Hayee, E Kobayashi, T Ozawa, T Fujii, A Muraguchi, K Tobe and H Kishi. 2021. TCR function analysis using a novel system reveals the multiple unconventional tumor-reactive T cells in human breast cancer-infiltrating lymphocytes. Eur J Immunol 51:2306-2316. DOI:10.1002/eji.202049070

5. N Tsugawa, D Yamada, T Watabe, M Onizawa, S Wang, Y Nemoto, S Oshima, T Tsubata, T Adachi, Y Kawano, M Watanabe, RS Blumberg, R Okamoto and T Nagaishi. 2021. CEACAM1 specifically suppresses B cell receptor signaling-mediated activation. Biochem Biophys Res Commun 535:99-105. DOI:10.1016/j.bbrc.2020.11.126

6. T Sakurai, M Kukimoto-Niino, K Kunimura, N Yamane, D Sakata, R Aihara, T Yasuda, S Yokoyama, M Shirouzu, Y Fukui and T Uruno. 2021. A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8. Life Sci Alliance 4:lsa.202000873. DOI:10.26508/lsa.202000873

7. S Osana, Y Kitajima, N Suzuki, A Nunomiya, H Takada, T Kubota, K Murayama and R Nagatomi. 2021. Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation. J Cell Physiol 236:5293-5305. DOI:10.1002/jcp.30237

8. A Nita, A Matsumoto, R Tang, C Shiraishi, K Ichihara, D Saito, M Suyama, T Yasuda, G Tsuji, M Furue, B Katayama, T Ozawa, T Murata, T Dainichi, K Kabashima, A Hatano, M Matsumoto and KI Nakayama. 2021. A ubiquitin-like protein encoded by the "noncoding" RNA TINCR promotes keratinocyte proliferation and wound healing. PLoS Genet 17:e1009686. DOI:10.1371/journal.pgen.1009686

9. M Mojic, K Shitaoka, C Ohshima, S Ucche, F Lyu, H Hamana, H Tahara, H Kishi and Y Hayakawa. 2021. NKG2D defines tumor-reacting effector CD8(+) T cells within tumor microenvironment. Cancer Sci 112:3484-3490. DOI:10.1111/cas.15050

10. WS Kong, N Tsuyama, H Inoue, Y Guo, S Mokuda, A Nobukiyo, N Nakatani, F Yamaide, T Nakano, Y Kohno, K Ikeda, Y Nakanishi, H Ohno, M Arita, N Shimojo and M Kanno. 2021. Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s. Sci Rep 11:13109. DOI:10.1038/s41598-021-92282-0

11. S Huang and T Yasuda. 2021. Pathologically Relevant Mouse Models for Epstein-Barr Virus-Associated B Cell Lymphoma. Front Immunol 12:639844. DOI:10.3389/fimmu.2021.639844

2020

12. K Yoshioka, Y Kitajima, N Okazaki, K Chiba, A Yonekura and Y Ono. 2020. A Modified Pre-plating Method for High-Yield and High-Purity Muscle Stem Cell Isolation From Human/Mouse Skeletal Muscle Tissues. Front Cell Dev Biol 8:793. DOI:10.3389/fcell.2020.00793

13. Y Yang, S Nagai, S Kang, Y Xia, Y Kawano, K Miyake, H Karasuyama and M Azuma. 2020. Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting. Int Immunol 32:509-518. DOI:10.1093/intimm/dxaa014

14. Y Tsuchiya, Y Kitajima, H Masumoto and Y Ono. 2020. Damaged Myofiber-Derived Metabolic Enzymes Act as Activators of Muscle Satellite Cells. Stem Cell Reports 15:926-940. DOI:10.1016/j.stemcr.2020.08.002

15. K Sukegawa, K Shitaoka, H Hamana, E Kobayashi, Y Miyahara, K Fujii, K Tsuda, S Saeki, T Nagata, T Ozawa, S Saito, T Fujii, A Muraguchi, H Shiku and H Kishi. 2020. Relationship between T cell receptor clonotype and PD-1 expression of tumor-infiltrating lymphocytes in colorectal cancer. Eur J Immunol 50:1580-1590. DOI:10.1002/eji.201948399

16. T Sommermann, T Yasuda, J Ronen, T Wirtz, T Weber, U Sack, R Caeser, J Zhang, X Li, VT Chu, A Jauch, K Unger, DJ Hodson, A Akalin and K Rajewsky. 2020. Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis. Proc Natl Acad Sci U S A 117:14421-14432. DOI:10.1073/pnas.1921139117

17. S Osana, Y Kitajima, N Suzuki, Y Xu, K Murayama and R Nagatomi. 2020. siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation. Exp Cell Res 397:112337. DOI:10.1016/j.yexcr.2020.112337

18. H Ono, N Suzuki, SI Kanno, G Kawahara, R Izumi, T Takahashi, Y Kitajima, S Osana, N Nakamura, T Akiyama, K Ikeda, T Shijo, S Mitsuzawa, R Nagatomi, N Araki, A Yasui, H Warita, YK Hayashi, K Miyake and M Aoki. 2020. AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy. Mol Ther 28:1133-1153. DOI:10.1016/j.ymthe.2020.02.006

19. Y Kitajima, K Yoshioka and N Suzuki. 2020. The ubiquitin-proteasome system in regulation of the skeletal muscle homeostasis and atrophy: from basic science to disorders. J Physiol Sci 70:40. DOI:10.1186/s12576-020-00768-9

20. Y Kitajima, N Suzuki, K Yoshioka, R Izumi, M Tateyama, Y Tashiro, R Takahashi, M Aoki and Y Ono. 2020. Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy. Front Cell Dev Biol 8:859. DOI:10.3389/fcell.2020.00859

21. M Furukawa, S Ohki, S Kitanobo, H Fukami and M Morita. 2020. Differences in spawning time drive cryptic speciation in the coral Acropora divaricata. Mar Biol 167:1-10. DOI:10.1007/s00227-020-03781-z

2019

22. S Yoshikawa, M Oh-Hora, R Hashimoto, T Nagao, L Peters, M Egawa, T Ohta, K Miyake, T Adachi, Y Kawano, Y Yamanishi and H Karasuyama. 2019. Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils. Sci Signal 12:eaav2060. DOI:10.1126/scisignal.aav2060

23. M Sato, S Hosoya, S Yoshikawa, S Ohki, Y Kobayashi, T Itou and K Kikuchi. 2019. A highly flexible and repeatable genotyping method for aquaculture studies based on target amplicon sequencing using next-generation sequencing technology. Sci Rep 9:6904. DOI:10.1038/s41598-019-43336-x

24. T Nagao, Y Yamanishi, K Miyake, M Teranishi, S Takahashi, S Yoshikawa, Y Kawano and H Karasuyama. 2019. Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice. Int Immunol 31:41-49. DOI:10.1093/intimm/dxy062

25. K Imami and T Yasuda. 2019. Measuring Protein Synthesis during Cell Cycle by Azidohomoalanine (AHA) Labeling and Flow Cytometric Analysis. Bio Protoc 9:e3215. DOI:10.21769/BioProtoc.3215

26. K Hosokawa, E Kobayashi, Y Akatsuka, L Espinoza, N Nakagawa, T Mikoto, N Tsuji, T Yoroidaka, H Mizumaki, TMA Nguyen, T Katagiri, K Shitaoka, H Hamana, H Kishi and S Nakao. 2019. Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia. Blood 134:3751. DOI:10.1182/blood-2019-125685

27. T Akiyama, N Suzuki, M Ishikawa, K Fujimori, T Sone, J Kawada, R Funayama, F Fujishima, S Mitsuzawa, K Ikeda, H Ono, T Shijo, S Osana, M Shirota, T Nakagawa, Y Kitajima, A Nishiyama, R Izumi, S Morimoto, Y Okada, T Kamei, M Nishida, M Nogami, S Kaneda, Y Ikeuchi, H Mitsuhashi, K Nakayama, T Fujii, H Warita, H Okano and M Aoki. 2019. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons. EBioMedicine 45:362-378. DOI:10.1016/j.ebiom.2019.06.013

2018

28. K Tsuda, H Kishi, A Nakashima, H Hamana, A Ushijima, S Tsuda, T Shima, K Shitaoka, E Kobayashi, T Ozawa, O Yoshino and S Saito. 2018. TCR repertoire analysis of cytotoxic T cell in peripheral blood in uterine endometrial cancer. Journal of Reproductive Immunology 130:44-44. DOI:10.1016/j.jri.2018.09.041

29. Y Tabakawa, T Ohta, S Yoshikawa, EJ Robinson, K Yamaji, K Ishiwata, Y Kawano, K Miyake, Y Yamanishi, H Ohtsu, T Adachi, N Watanabe, H Kanuka and H Karasuyama. 2018. Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice. Front Immunol 9:1540. DOI:10.3389/fimmu.2018.01540

30. K Shitaoka, H Hamana, H Kishi, Y Hayakawa, E Kobayashi, K Sukegawa, X Piao, F Lyu, T Nagata, D Sugiyama, H Nishikawa, A Tanemura, I Katayama, M Murahashi, Y Takamatsu, K Tani, T Ozawa and A Muraguchi. 2018. Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis. Cancer Immunol Res 6:378-388. DOI:10.1158/2326-6066.CIR-17-0489

31. T Shijo, H Warita, N Suzuki, Y Kitajima, K Ikeda, T Akiyama, H Ono, S Mitsuzawa, A Nishiyama, R Izumi and M Aoki. 2018. Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis. J Neurosci Res 96:222-233. DOI:10.1002/jnr.24127

32. T Shijo, H Warita, N Suzuki, K Ikeda, S Mitsuzawa, T Akiyama, H Ono, A Nishiyama, R Izumi, Y Kitajima and M Aoki. 2018. Antagonizing bone morphogenetic protein 4 attenuates disease progression in a rat model of amyotrophic lateral sclerosis. Exp Neurol 307:164-179. DOI:10.1016/j.expneurol.2018.06.009

33. G Petkau, Y Kawano, I Wolf, M Knoll and F Melchers. 2018. MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice. Eur J Immunol 48:975-989. DOI:10.1002/eji.201747354

34. S Ohki, T Hagi, K Nakano, A Shiroma, H Tamotsu, M Shimoji, M Shinzato, N Ashimine, M Minami, T Nakanishi, K Teruya, K Satou, N Moriya, M Kobayashi, M Nomura, C Suzuki and T Hirano. 2018. Complete Genome Sequence of Carotenoid-Producing Enterococcus gilvus CR1, Isolated from Raw Cow's Milk. Microbiol Resour Announc 7:e00988-00918. DOI:10.1128/MRA.00988-18

35. K Nakano, M Minami, M Shinzato, M Shimoji, N Ashimine, A Shiroma, S Ohki, T Nakanishi, H Tamotsu, K Teruya, K Satou, N Moriya, H Kimoto-Nira, M Kobayashi, T Hagi, M Nomura, C Suzuki and T Hirano. 2018. Complete Genome Sequence of Lactococcus lactis subsp. lactis G50 with Immunostimulating Activity, Isolated from Napier Grass. Genome Announc 6:e00069-00018. DOI:10.1128/genomeA.00069-18

36. N Moriya, K Nakano, A Shiroma, M Shinzato, N Ashimine, M Minami, H Tamotsu, M Shimoji, T Nakanishi, S Ohki, K Teruya, K Satou, T Hirano, T Hagi, M Kobayashi, M Nomura, H Kimoto-Nira, K Tajima, Y Cai and C Suzuki. 2018. Complete Genome Sequence of Lactobacillus plantarum Strain LQ80, Selected for Preparation of Fermented Liquid Feed for Pigs. Genome Announc 6:e00530-00518. DOI:10.1128/genomeA.00530-18

37. Y Kitajima, N Suzuki, A Nunomiya, S Osana, K Yoshioka, Y Tashiro, R Takahashi, Y Ono, M Aoki and R Nagatomi. 2018. The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells. Stem Cell Reports 11:1523-1538. DOI:10.1016/j.stemcr.2018.10.009

38. Y Kitajima and Y Ono. 2018. Visualization of PAX7 protein dynamics in muscle satellite cells in a YFP knock-in-mouse line. Skelet Muscle 8:26. DOI:10.1186/s13395-018-0174-x

39. Y Kawano, G Petkau, C Stehle, P Durek, GA Heinz, K Tanimoto, H Karasuyama, MF Mashreghi, C Romagnani and F Melchers. 2018. Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors. Blood 131:2026-2035. DOI:10.1182/blood-2017-09-805259

40. H Karasuyama, K Miyake, S Yoshikawa, Y Kawano and Y Yamanishi. 2018. How do basophils contribute to Th2 cell differentiation and allergic responses? Int Immunol 30:391-396. DOI:10.1093/intimm/dxy026

41. K Imami, M Milek, B Bogdanow, T Yasuda, N Kastelic, H Zauber, Y Ishihama, M Landthaler and M Selbach. 2018. Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis. Mol Cell 72:84-98 e89. DOI:10.1016/j.molcel.2018.08.019

42. K Ikegami, Y Aita, A Shiroma, M Shimoji, H Tamotsu, N Ashimine, M Shinzato, S Ohki, K Nakano, K Teruya, K Satou, T Hirano and M Yohda. 2018. Complete Genome Sequence of Petrimonas sp. Strain IBARAKI, Assembled from the Metagenome Data of a Culture Containing Dehalococcoides spp. Genome Announc 6:e00384-00318. DOI:10.1128/genomeA.00384-18

43. VM Ho, N Hirohashi, WS Kong, G Yun, K Ota, J Itai, S Yamaga, K Suzuki, K Tanigawa, M Kanno and N Shime. 2018. Sera from Septic Patients Contain the Inhibiting Activity of the Extracellular ATP-Dependent Inflammasome Pathway. Tohoku J Exp Med 245:193-204. DOI:10.1620/tjem.245.193

44. A Harada, K Maehara, Y Ono, H Taguchi, K Yoshioka, Y Kitajima, Y Xie, Y Sato, T Iwasaki, J Nogami, S Okada, T Komatsu, Y Semba, T Takemoto, H Kimura, H Kurumizaka and Y Ohkawa. 2018. Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun 9:1400. DOI:10.1038/s41467-018-03845-1

45. S Fujimaki, D Seko, Y Kitajima, K Yoshioka, Y Tsuchiya, S Masuda and Y Ono. 2018. Notch1 and Notch2 Coordinately Regulate Stem Cell Function in the Quiescent and Activated States of Muscle Satellite Cells. Stem Cells 36:278-285. DOI:10.1002/stem.2743

46. Y Asahina, A Shiroma, K Nakano, H Tamotsu, N Ashimine, M Shinzato, M Minami, M Shimoji, T Nakanishi, S Ohki, K Teruya, K Satou, M Kobayashi, T Hagi, N Moriya, C Suzuki, A Tajima, M Nomura and T Hirano. 2018. Complete Genome Sequence of Lactobacillus paracasei EG9, a Strain Accelerating Free Amino Acid Production during Cheese Ripening. Genome Announc 6:e00627-00618. DOI:10.1128/genomeA.00627-18

2017

47. M Yohda, K Ikegami, Y Aita, M Kitajima, A Takechi, M Iwamoto, T Fukuda, N Tamura, J Shibasaki, S Koike, D Komatsu, S Miyagi, M Nishimura, Y Uchino, A Shiroma, M Shimoji, H Tamotsu, N Ashimine, M Shinzato, S Ohki, K Nakano, K Teruya, K Satou, T Hirano and O Yagi. 2017. Isolation and genomic characterization of a Dehalococcoides strain suggests genomic rearrangement during culture. Sci Rep 7:2230. DOI:10.1038/s41598-017-02381-0

48. J Tornack, Y Kawano, N Garbi, GJ Hammerling, F Melchers and M Tsuneto. 2017. Flt3 ligand-eGFP-reporter expression characterizes functionally distinct subpopulations of CD150(+) long-term repopulating murine hematopoietic stem cells. Eur J Immunol 47:1477-1487. DOI:10.1002/eji.201646730

49. T Ohta, S Yoshikawa, Y Tabakawa, K Yamaji, K Ishiwata, H Shitara, C Taya, M Oh-Hora, Y Kawano, K Miyake, Y Yamanishi, H Yonekawa, N Watanabe, H Kanuka and H Karasuyama. 2017. Skin CD4(+) Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites. Front Immunol 8:1348. DOI:10.3389/fimmu.2017.01348

50. A Nunomiya, J Shin, Y Kitajima, T Dan, T Miyata and R Nagatomi. 2017. Activation of the hypoxia-inducible factor pathway induced by prolyl hydroxylase domain 2 deficiency enhances the effect of running training in mice. Acta Physiol (Oxf) 220:99-112. DOI:10.1111/apha.12751

51. K Nakano, A Shiroma, M Shimoji, H Tamotsu, N Ashimine, S Ohki, M Shinzato, M Minami, T Nakanishi, K Teruya, K Satou and T Hirano. 2017. Advantages of genome sequencing by long-read sequencer using SMRT technology in medical area. Hum Cell 30:149-161. DOI:10.1007/s13577-017-0168-8

52. Y Kawano, G Petkau, I Wolf, J Tornack and F Melchers. 2017. IL-7 and immobilized Kit-ligand stimulate serum- and stromal cell-free cultures of precursor B-cell lines and clones. Eur J Immunol 47:206-212. DOI:10.1002/eji.201646677

2016

53. T Wirtz, T Weber, S Kracker, T Sommermann, K Rajewsky and T Yasuda. 2016. Mouse model for acute Epstein-Barr virus infection. Proc Natl Acad Sci U S A 113:13821-13826. DOI:10.1073/pnas.1616574113

54. A Uruno, Y Yagishita, F Katsuoka, Y Kitajima, A Nunomiya, R Nagatomi, J Pi, SS Biswal and M Yamamoto. 2016. Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism. Mol Cell Biol 36:1655-1672. DOI:10.1128/MCB.01095-15

55. H Shinohara, T Yasuda and T Kurosaki. 2016. TAK1 adaptor proteins, TAB2 and TAB3, link the signalosome to B-cell receptor-induced IKK activation. FEBS Lett 590:3264-3269. DOI:10.1002/1873-3468.12342

56. J Shin, A Nunomiya, Y Kitajima, T Dan, T Miyata and R Nagatomi. 2016. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle 6:5. DOI:10.1186/s13395-016-0079-5

57. X Piao, T Ozawa, H Hamana, K Shitaoka, A Jin, H Kishi and A Muraguchi. 2016. TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo. Oncoimmunology 5:e1131380. DOI:10.1080/2162402X.2015.1131380

58. K Nakano, A Shiroma, H Tamotsu, S Ohki, M Shimoji, N Ashimine, M Shinzato, M Minami, T Nakanishi, K Teruya, K Satou, C Suzuki, H Kimoto-Nira, M Kobayashi, K Mizumachi, R Aoki, S Miyata, K Yamamoto, Y Ohtake, T Eguchi-Ogawa, N Moriya, T Hagi, M Nomura and T Hirano. 2016. First Complete Genome Sequence of the Skin-Improving Lactobacillus curvatus Strain FBA2, Isolated from Fermented Vegetables, Determined by PacBio Single-Molecule Real-Time Technology. Genome Announc 4:e00884-00816. DOI:10.1128/genomeA.00884-16

59. DJ Klionsky, ... Y Kitajima, ... and SM Zughaier. 2016. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12:1-222. DOI:10.1080/15548627.2015.1100356

60. Y Kitajima, S Ogawa and Y Ono. 2016. Visualizing the Functional Heterogeneity of Muscle Stem Cells. Methods Mol Biol 1516:183-193. DOI:10.1007/7651_2016_349

61. E Ishikawa, H Kosako, T Yasuda, M Ohmuraya, K Araki, T Kurosaki, T Saito and S Yamasaki. 2016. Protein kinase D regulates positive selection of CD4(+) thymocytes through phosphorylation of SHP-1. Nat Commun 7:12756. DOI:10.1038/ncomms12756

62. H Hamana, K Shitaoka, H Kishi, T Ozawa and A Muraguchi. 2016. A novel, rapid and efficient method of cloning functional antigen-specific T-cell receptors from single human and mouse T-cells. Biochem Biophys Res Commun 474:709-714. DOI:10.1016/j.bbrc.2016.05.015

63. E Derudder, S Herzog, V Labi, T Yasuda, K Kochert, M Janz, A Villunger, M Schmidt-Supprian and K Rajewsky. 2016. Canonical NF-kappaB signaling is uniquely required for the long-term persistence of functional mature B cells. Proc Natl Acad Sci U S A 113:5065-5070. DOI:10.1073/pnas.1604529113

64. S Cho, CJ Wu, T Yasuda, LO Cruz, AA Khan, LL Lin, DT Nguyen, M Miller, HM Lee, ML Kuo, DH Broide, K Rajewsky, AY Rudensky and LF Lu. 2016. miR-23 approximately 27 approximately 24 clusters control effector T cell differentiation and function. J Exp Med 213:235-249. DOI:10.1084/jem.20150990

2015

65. T Yasuda. 2015. MAP kinase cascades in antigen receptor signaling and physiology. Current Topics in Microbiology and Immunology 393:211-231. DOI:10.1007/82_2015_481

66. M Yamaya, Y Shimotai, Y Hatachi, N Lusamba Kalonji, Y Tando, Y Kitajima, K Matsuo, H Kubo, R Nagatomi, S Hongo, M Homma and H Nishimura. 2015. The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells. Pulm Pharmacol Ther 33:66-74. DOI:10.1016/j.pupt.2015.07.001

67. A Shiroma, Y Terabayashi, K Nakano, M Shimoji, H Tamotsu, N Ashimine, S Ohki, M Shinzato, K Teruya, K Satou and T Hirano. 2015. First Complete Genome Sequences of Staphylococcus aureus subsp. aureus Rosenbach 1884 (DSM 20231T), Determined by PacBio Single-Molecule Real-Time Technology. Genome Announc 3:e00800-00815. DOI:10.1128/genomeA.00800-15

68. K Satou, M Shimoji, H Tamotsu, A Juan, N Ashimine, M Shinzato, C Toma, T Nohara, A Shiroma, K Nakano, K Teruya, Y Terabayashi, S Ohki, N Koizumi, S Okano, T Suzuki and T Hirano. 2015. Complete Genome Sequences of Low-Passage Virulent and High-Passage Avirulent Variants of Pathogenic Leptospira interrogans Serovar Manilae Strain UP-MMC-NIID, Originally Isolated from a Patient with Severe Leptospirosis, Determined Using PacBio Single-Molecule Real-Time Technology. Genome Announc 3:e00882-00815. DOI:10.1128/genomeA.00882-15

69. S Sander, VT Chu, T Yasuda, A Franklin, R Graf, DP Calado, S Li, K Imami, M Selbach, M Di Virgilio, L Bullinger and K Rajewsky. 2015. PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones. Immunity 43:1075-1086. DOI:10.1016/j.immuni.2015.10.021

70. S Ohki, RK Kowalski, S Kitanobo and M Morita. 2015. Changes in spawning time led to the speciation of the broadcast spawning corals Acropora digitifera and the cryptic species Acropora sp 1 with similar gamete recognition systems. Coral Reefs 34:1189-1198. DOI:10.1007/s00338-015-1337-4

71. K Nakano, Y Terabayashi, A Shiroma, M Shimoji, H Tamotsu, N Ashimine, S Ohki, M Shinzato, K Teruya, K Satou and T Hirano. 2015. First Complete Genome Sequence of Clostridium sporogenes DSM 795T, a Nontoxigenic Surrogate for Clostridium botulinum, Determined Using PacBio Single-Molecule Real-Time Technology. Genome Announc 3:e00832-00815. DOI:10.1128/genomeA.00832-15

72. K Nakano, Y Terabayashi, A Shiroma, M Shimoji, H Tamotsu, N Ashimine, S Ohki, M Shinzato, K Teruya, K Satou and T Hirano. 2015. First Complete Genome Sequence of Pseudomonas aeruginosa (Schroeter 1872) Migula 1900 (DSM 50071T), Determined Using PacBio Single-Molecule Real-Time Technology. Genome Announc 3:e00932-00915. DOI:10.1128/genomeA.00932-15

73. Y Murakawa, M Hinz, J Mothes, A Schuetz, M Uhl, E Wyler, T Yasuda, G Mastrobuoni, CC Friedel, L Dolken, S Kempa, M Schmidt-Supprian, N Bluthgen, R Backofen, U Heinemann, J Wolf, C Scheidereit and M Landthaler. 2015. RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kappaB pathway. Nat Commun 6:7367. DOI:10.1038/ncomms8367

74. Z Mou, J Li, T Boussoffara, H Kishi, H Hamana, P Ezzati, C Hu, W Yi, D Liu, F Khadem, I Okwor, P Jia, K Shitaoka, S Wang, M Ndao, C Petersen, J Chen, S Rafati, H Louzir, A Muraguchi, JA Wilkins and JE Uzonna. 2015. Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4+ T cells. Sci Transl Med 7:310ra167. DOI:10.1126/scitranslmed.aac5477

75. S Mokuda, T Miyazaki, Y Ito, S Yamasaki, H Inoue, Y Guo, WS Kong, M Kanno, K Takasugi, E Sugiyama and J Masumoto. 2015. The proto-oncogene survivin splice variant 2B is induced by PDGF and leads to cell proliferation in rheumatoid arthritis fibroblast-like synoviocytes. Sci Rep 5:9795. DOI:10.1038/srep09795

76. L LiHua, S Yoshikawa, T Ohta, K Horiguchi, Y Kawano, H Ohtsu, Y Yamanishi and H Karasuyama. 2015. Large particulate allergens can elicit mast cell-mediated anaphylaxis without exit from blood vessels as efficiently as do small soluble allergens. Biochem Biophys Res Commun 467:70-75. DOI:10.1016/j.bbrc.2015.09.120

77. H Kishi, H Hamana, K Shitaoka and A Muraguchi. 2015. Identification of tumor-specific T cell receptors from primary tumor-infiltrating lymphocytes. Journal for ImmunoTherapy of Cancer 3:1-1. DOI:10.1186/2051-1426-3-s2-p74

2014

78. S Yasukawa, Y Miyazaki, C Yoshii, M Nakaya, N Ozaki, S Toda, E Kuroda, K Ishibashi, T Yasuda, Y Natsuaki, F Mi-ichi, E Iizasa, T Nakahara, M Yamazaki, K Kabashima, Y Iwakura, T Takai, T Saito, T Kurosaki, B Malissen, N Ohno, M Furue, H Yoshida and H Hara. 2014. An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells. Nat Commun 5:3755. DOI:10.1038/ncomms4755

79. H Shinohara, M Behar, K Inoue, M Hiroshima, T Yasuda, T Nagashima, S Kimura, H Sanjo, S Maeda, N Yumoto, S Ki, S Akira, Y Sako, A Hoffmann, T Kurosaki and M Okada-Hatakeyama. 2014. Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-kappaB activation. Science 344:760-764. DOI:10.1126/science.1250020

80. S Ohki, M Morita, S Kitanobo, AA Kowalska and RK Kowalski. 2014. Cryopreservation of Acropora digitifera sperm with use of sucrose and methanol based solution. Cryobiology 69:134-139. DOI:10.1016/j.cryobiol.2014.06.005

81. Y Kitajima, Y Tashiro, N Suzuki, H Warita, M Kato, M Tateyama, R Ando, R Izumi, M Yamazaki, M Abe, K Sakimura, H Ito, M Urushitani, R Nagatomi, R Takahashi and M Aoki. 2014. Proteasome dysfunction induces muscle growth defects and protein aggregation. J Cell Sci 127:5204-5217. DOI:10.1242/jcs.150961

2013

82. T Yasuda, T Wirtz, B Zhang, T Wunderlich, M Schmidt-Supprian, T Sommermann and K Rajewsky. 2013. Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice. Cold Spring Harbor Symposia on Quantitative Biology 78:259-263. DOI:10.1101/sqb.2013.78.020222

83. S Ohki, T Irie, M Inoue, K Shinmen, H Kawahata, T Nakamura, A Kato, Y Nojiri, A Suzuki, K Sakai and R van Woesik. 2013. Calcification responses of symbiotic and aposymbiotic corals to near-future levels of ocean acidification. Biogeosciences 10:6807-6814. DOI:10.5194/bg-10-6807-2013

84. K Obata-Ninomiya, K Ishiwata, H Tsutsui, Y Nei, S Yoshikawa, Y Kawano, Y Minegishi, N Ohta, N Watanabe, H Kanuka and H Karasuyama. 2013. The skin is an important bulwark of acquired immunity against intestinal helminths. J Exp Med 210:2583-2595. DOI:10.1084/jem.20130761

85. A Farmawati, Y Kitajima, T Nedachi, M Sato, M Kanzaki and R Nagatomi. 2013. Characterization of contraction-induced IL-6 up-regulation using contractile C2C12 myotubes. Endocr J 60:137-147. DOI:10.1507/endocrj.ej12-0316

86. M Egawa, K Mukai, S Yoshikawa, M Iki, N Mukaida, Y Kawano, Y Minegishi and H Karasuyama. 2013. Inflammatory monocytes recruited to allergic skin acquire an anti-inflammatory M2 phenotype via basophil-derived interleukin-4. Immunity 38:570-580. DOI:10.1016/j.immuni.2012.11.014

2012

87. B Zhang, S Kracker, T Yasuda, S Casola, M Vanneman, C Homig-Holzel, Z Wang, E Derudder, S Li, T Chakraborty, SE Cotter, S Koyama, T Currie, GJ Freeman, JL Kutok, SJ Rodig, G Dranoff and K Rajewsky. 2012. Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model. Cell 148:739-751. DOI:10.1016/j.cell.2011.12.031

88. H Ogawa, K Mukai, Y Kawano, Y Minegishi and H Karasuyama. 2012. Th2-inducing cytokines IL-4 and IL-33 synergistically elicit the expression of transmembrane TNF-alpha on macrophages through the autocrine action of IL-6. Biochem Biophys Res Commun 420:114-118. DOI:10.1016/j.bbrc.2012.02.124

89. T Kurogi, H Inoue, Y Guo, A Nobukiyo, K Nohara and M Kanno. 2012. A methyl-deficient diet modifies early B cell development. Pathobiology 79:209-218. DOI:10.1159/000337290

90. Y Kawano, R Ouchida, JY Wang, S Yoshikawa, M Yamamoto, D Kitamura and H Karasuyama. 2012. A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 5. Mol Cell Biol 32:4462-4471. DOI:10.1128/MCB.00531-12

2011

91. T Yasuda, K Kometani, N Takahashi, Y Imai, Y Aiba and T Kurosaki. 2011. ERKs induce expression of the transcriptional repressor Blimp-1 and subsequent plasma cell differentiation. Sci Signal 4:ra25. DOI:10.1126/scisignal.2001592

92. H Yamagishi, Y Mochizuki, T Hamakubo, K Obata, T Ugajin, S Sato, Y Kawano, Y Minegishi and H Karasuyama. 2011. Basophil-derived mouse mast cell protease 11 induces microvascular leakage and tissue edema in a mast cell-independent manner. Biochem Biophys Res Commun 415:709-713. DOI:10.1016/j.bbrc.2011.10.150

93. H Nishikado, K Mukai, Y Kawano, Y Minegishi and H Karasuyama. 2011. NK cell-depleting anti-asialo GM1 antibody exhibits a lethal off-target effect on basophils in vivo. J Immunol 186:5766-5771. DOI:10.4049/jimmunol.1100370

94. M Nakamura, S Ohki, A Suzuki and K Sakai. 2011. Coral larvae under ocean acidification: survival, metabolism, and metamorphosis. Plos One 6:e14521. DOI:10.1371/journal.pone.0014521

95. Y Guo, M Miyazaki, M Itoi, R Satoh, A Iwama, T Amagai, H Kawamoto and M Kanno. 2011. Polycomb group gene Bmi1 plays a role in the growth of thymic epithelial cells. Eur J Immunol 41:1098-1107. DOI:10.1002/eji.201040794

2010

96. T Wada, K Ishiwata, H Koseki, T Ishikura, T Ugajin, N Ohnuma, K Obata, R Ishikawa, S Yoshikawa, K Mukai, Y Kawano, Y Minegishi, H Yokozeki, N Watanabe and H Karasuyama. 2010. Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks. J Clin Invest 120:2867-2875. DOI:10.1172/JCI42680

97. K Miyazaki, M Miyazaki, Y Guo, N Yamasaki, M Kanno, Z Honda, H Oda, H Kawamoto and H Honda. 2010. The role of the basic helix-loop-helix transcription factor Dec1 in the regulatory T cells. J Immunol 185:7330-7339. DOI:10.4049/jimmunol.1001381

98. S Kuchen, W Resch, A Yamane, N Kuo, Z Li, T Chakraborty, L Wei, A Laurence, T Yasuda, S Peng, J Hu-Li, K Lu, W Dubois, Y Kitamura, N Charles, HW Sun, S Muljo, PL Schwartzberg, WE Paul, J O'Shea, K Rajewsky and R Casellas. 2010. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity 32:828-839. DOI:10.1016/j.immuni.2010.05.009

99. R Ishikawa, Y Tsujimura, K Obata, Y Kawano, Y Minegishi and H Karasuyama. 2010. IgG-mediated systemic anaphylaxis to protein antigen can be induced even under conditions of limited amounts of antibody and antigen. Biochem Biophys Res Commun 402:742-746. DOI:10.1016/j.bbrc.2010.10.098

2009

100. S Yoshikawa, Y Kawano, Y Minegishi and H Karasuyama. 2009. The skewed heavy-chain repertoire in peritoneal B-1 cells is predetermined by the selection via pre-B cell receptor during B cell ontogeny in the fetal liver. Int Immunol 21:43-52. DOI:10.1093/intimm/dxn122

101. T Ugajin, T Kojima, K Mukai, K Obata, Y Kawano, Y Minegishi, Y Eishi, H Yokozeki and H Karasuyama. 2009. Basophils preferentially express mouse Mast Cell Protease 11 among the mast cell tryptase family in contrast to mast cells. J Leukoc Biol 86:1417-1425. DOI:10.1189/jlb.0609400

2008

102. T Yasuda, H Sanjo, G Pages, Y Kawano, H Karasuyama, J Pouyssegur, M Ogata and T Kurosaki. 2008. Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity 28:499-508. DOI:10.1016/j.immuni.2008.02.015

103. T Yasuda and T Kurosaki. 2008. Regulation of lymphocyte fate by Ras/ERK signals. Cell Cycle 7:3634-3640. DOI:10.4161/cc.7.23.7103

104. Y Tsujimura, K Obata, K Mukai, H Shindou, M Yoshida, H Nishikado, Y Kawano, Y Minegishi, T Shimizu and H Karasuyama. 2008. Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity 28:581-589. DOI:10.1016/j.immuni.2008.02.008

105. M Miyazaki, K Miyazaki, M Itoi, Y Katoh, Y Guo, R Kanno, Y Katoh-Fukui, H Honda, T Amagai, M van Lohuizen, H Kawamoto and M Kanno. 2008. Thymocyte proliferation induced by pre-T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression. Immunity 28:231-245. DOI:10.1016/j.immuni.2007.12.013

106. T Hosooka, T Noguchi, K Kotani, T Nakamura, H Sakaue, H Inoue, W Ogawa, K Tobimatsu, K Takazawa, M Sakai, Y Matsuki, R Hiramatsu, T Yasuda, MA Lazar, Y Yamanashi and M Kasuga. 2008. Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation. Nat Med 14:188-193. DOI:10.1038/nm1706

2007

107. T Yasuda, K Bundo, A Hino, K Honda, A Inoue, M Shirakata, M Osawa, T Tamura, H Nariuchi, H Oda, T Yamamoto and Y Yamanashi. 2007. Dok-1 and Dok-2 are negative regulators of T cell receptor signaling. Int Immunol 19:487-495. DOI:10.1093/intimm/dxm015

108. K Obata, K Mukai, Y Tsujimura, K Ishiwata, Y Kawano, Y Minegishi, N Watanabe and H Karasuyama. 2007. Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood 110:913-920. DOI:10.1182/blood-2007-01-068718

109. Y Matsubara, I Kawasaki, S Urushiyama, T Yasuda, M Shirakata, Y Iino, H Shibuya and Y Yamanashi. 2007. The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans. Genes Cells 12:407-420. DOI:10.1111/j.1365-2443.2007.01061.x

110. A Inoue, T Yasuda, T Yamamoto and Y Yamanashi. 2007. Dok-1 is a positive regulator of IL-4 signalling and IgE response. J Biochem 142:257-263. DOI:10.1093/jb/mvm127

2006

111. M Yamamoto, K Hayashi, T Nojima, Y Matsuzaki, Y Kawano, H Karasuyama, R Goitsuka and D Kitamura. 2006. BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces kappa gene rearrangement. Blood 108:2703-2711. DOI:10.1182/blood-2006-05-024968

112. Y Kawano, S Yoshikawa, Y Minegishi and H Karasuyama. 2006. Pre-B cell receptor assesses the quality of IgH chains and tunes the pre-B cell repertoire by delivering differential signals. J Immunol 177:2242-2249. DOI:10.4049/jimmunol.177.4.2242

113. M Honma, O Higuchi, M Shirakata, T Yasuda, H Shibuya, S Iemura, T Natsume and Y Yamanashi. 2006. Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases. Genes Cells 11:143-151. DOI:10.1111/j.1365-2443.2006.00926.x

2005

114. H Shinohara, T Yasuda, Y Aiba, H Sanjo, M Hamadate, H Watarai, H Sakurai and T Kurosaki. 2005. PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1. J Exp Med 202:1423-1431. DOI:10.1084/jem.20051591

115. H Shinohara, A Inoue, N Toyama-Sorimachi, Y Nagai, T Yasuda, H Suzuki, R Horai, Y Iwakura, T Yamamoto, H Karasuyama, K Miyake and Y Yamanashi. 2005. Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling. J Exp Med 201:333-339. DOI:10.1084/jem.20041817

116. Y Kawano, S Yoshikawa, Y Minegishi and H Karasuyama. 2005. Selection of stereotyped VH81X-{micro}H chains via pre-B cell receptor early in ontogeny and their conservation in adults by marginal zone B cells. Int Immunol 17:857-867. DOI:10.1093/intimm/dxh265

117. Y Katakura, K Yoshizaki, T Yasuda, T Tsunematsu, N Uehara, T Miura, T Fujiki and S Shirahata. 2005. Functional impairment of telomerase in sublines derived from human lung adenocarcinoma exposed to mild oxidative stress. Biochem Biophys Res Commun 334:450-459. DOI:10.1016/j.bbrc.2005.06.109

2004

118. T Yasuda and T Yamamoto. 2004. Analysis of B-cell signaling using DT40 B-cell line. Methods Mol Biol 271:261-270. DOI:10.1385/1-59259-796-3:261

119. T Yasuda, M Shirakata, A Iwama, A Ishii, Y Ebihara, M Osawa, K Honda, H Shinohara, K Sudo, K Tsuji, H Nakauchi, Y Iwakura, H Hirai, H Oda, T Yamamoto and Y Yamanashi. 2004. Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia. J Exp Med 200:1681-1687. DOI:10.1084/jem.20041247

120. H Shinohara, T Yasuda and Y Yamanashi. 2004. Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding. Genes Cells 9:601-607. DOI:10.1111/j.1356-9597.2004.00748.x

2003

121. K Tsuchiya, Y Kawano, T Kojima, K Nagata, T Takao, M Okada, H Shinohara, K Maki, N Toyama-Sorimachi, N Miyasaka, M Watanabe and H Karasuyama. 2003. Molecular cloning and characterization of TPP36 and its isoform TPP32, novel substrates of Abl tyrosine kinase. FEBS Lett 537:203-209. DOI:10.1016/s0014-5793(03)00127-3

2002

122. K Yokoyama, IH Su Ih, T Tezuka, T Yasuda, K Mikoshiba, A Tarakhovsky and T Yamamoto. 2002. BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor. EMBO J 21:83-92. DOI:10.1093/emboj/21.1.83

123. T Yasuda, T Tezuka, A Maeda, T Inazu, Y Yamanashi, H Gu, T Kurosaki and T Yamamoto. 2002. Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells. J Exp Med 196:51-63. DOI:10.1084/jem.20020068

124. M Magari, T Sawatari, Y Kawano, M Cascalho, M Wabl, N Kanayama, M Hikida and H Ohmori. 2002. Contribution of light chain rearrangement in peripheral B cells to the generation of high-affinity antibodies. Eur J Immunol 32:957-966. DOI:10.1002/1521-4141(200204)32:4<957::AID-IMMU957>3.0.CO;2-A

2000

125. T Yasuda, A Maeda, M Kurosaki, T Tezuka, K Hironaka, T Yamamoto and T Kurosaki. 2000. Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding. J Exp Med 191:641-650. DOI:10.1084/jem.191.4.641

1997

126. Y Katakura, K Yamamoto, O Miyake, T Yasuda, N Uehara, E Nakata, S Kawamoto and S Shirahata. 1997. Bidirectional regulation of telomerase activity in a subline derived from human lung adenocarcinoma. Biochem Biophys Res Commun 237:313-317. DOI:10.1006/bbrc.1997.7104

競争的研究費取得状況

保田朋波流
1.2021-2023年度 基盤研究(B)「免疫特性と癌化に及ぼすリンパ球増殖限界のエピジェネティックな制御基盤」
2. 2019-2020年度 挑戦的研究(萌芽)「体細胞寿命および新旧細胞間相互作用の解析」
3.2018-2020年度 基盤研究(B)「免疫特性と癌化に及ぼすリンパ球増殖限界制御の分子基盤」
4. 2017-2018年度 研究活動スタート支援「癌化と感染防御におけるB細胞増殖限界制御の分子基盤」
5. 2017年度 九州大学QRプログラム(わかばチャレンジ)「免疫細胞の増殖限界制御機構の解明」
6. 2017年度 公益信託 日本白血病研究基金「リンパ腫発症における細胞老化因子の解析」
7. 2017年度 公益財団法人 先進医薬研究振興財団(血液医学分野研究助成)「免疫細胞の増殖限界制御の分子基盤」
8. 2008-2009年度 若手研究(B)「T細胞依存性抗原に対するB細胞応答におけるErkの役割の解明」
9. 2006-2007年度 若手研究(B)「BCR下流のアダプター分子BLNKと会合する新規シグナル分子の機能解析」

河野洋平
1. 2020年度 武田薬品工業(COCKPI-T) 「cCLPを利用した効率的かつ大量の免疫寛容誘導性形質樹状細胞取得法の開発」
2. 2019年度 公益財団法人 先進医薬研究振興財団 血液医学分野研究助成「cCLPの増殖維持に関わる支持細胞由来因子の同定」
3. 2018-2020年度 武田科学振興財団 医学研究助成「新規生体機能遺伝子スクリーニング法を用いたアレルギー性炎症抑制機構の解明」
4. 2014-2015年度Humboldt Research Fellowship for Experienced Researchers 「Identification of exogenous factors to improve the generation of pluripotent hematopoietic stem cells from embryonic stem cells」
5. 2011-2013年度 文部科学省科学研究費補助金 若手研究(B)「プレBCRダウンレギュレーションにおけるリソソーム膜分子Laptm5の役割」
6. 2009-2011年度 文部科学省科学研究費補助金 若手研究(B)「プレB細胞レセプターの発現制御機構と急性リンパ性白血病化の解明」
7. 2006-2008年度 文部科学省科学研究費 若手研究(B)「プレB細胞レセプターの発現調節機構の解明」

郭芸
1. 2017-2018年度 若手研究(B)「The regulation of the ubiquitin-editing protein A20 in thymic selection」
2. 2013年度 広島大学女性研究者奨励賞 「NF-kB シグナルソームのユビキチン制御蛋白質A20 による、免疫反応・炎症の解析と免疫老化の関係」

下岡清美
1. 2018-2019年度 若手研究「腫瘍浸潤Tリンパ球のT細胞受容体のがん特異性の検証と新規がん抗原の同定」

北嶋康雄
1. 2020-2024年度 文部科学省 卓越研究員事業卓越研究員「骨格筋再生における包括的な制御機構の解明」
2. 2020-2023年度 基盤研究(B)「骨格筋再生における筋幹細胞の新たなダイナミクスの解明」
3. 2020-2021年度 公益財団法人 武田科学振興財団「加齢性筋肉減弱症の予防・改善のための骨格筋幹細胞の維持機構の解明」
4. 2020年度 公益財団法人 鈴木謙三記念医科学応用研究財団「加齢性筋肉減弱症の病態解明における骨格筋幹細胞の基礎的研究」
5. 2018-2019年度 若手研究「骨格筋幹細胞における老化制御機構の解明」
6. 2018年度 公益財団法人 上原記念生命科学財団「骨格筋幹細胞における老化機構の解明に関する研究」
7. 2017年度 公益財団法人 中冨健康科学振興財団「骨格筋再生過程におけるタンパク分解機構の役割解明に関する研究」
8. 2016年度 公益財団法人 明治安田厚生事業団「骨格筋量を決定するタンパク分解系に着目した筋再生メカニズムの解明に関する研究」
9. 2016-2018年度 日本学術振興会 特別研究員SPD奨励費「タンパク分解系に着目した筋幹細胞調節機構の解明」
10. 2015年度 公益財団法人 ヤマハ発動機研究助成「骨格筋萎縮時における筋代謝特性の解明-骨格筋代謝物質の網羅解析による検証-」
11. 2015-2018年度 若手研究(B)「骨格筋におけるプロテアソームの筋量調節機構の解明」
12. 2013年度 公益財団法人 日本科学協会「骨格筋量決定における蛋白分解処理機構の役割」

河原隆浩
1. 2020年度 公益財団法人 ニッポンハム食の未来財団(個人研究助成)「経皮感作食物アレルギーモデル確立と脂肪酸摂取によるアレルギー制御」